Harstad, Eric: search on Z-Library

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1

Pharmacokinetic drivers of toxicity for basic molecules: Strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor

Dolores Diaz, Kevin A. Ford, Dylan P. Hartley, Eric B. Harstad, Gary R. Cain, Kirsten Achilles-Poon, Trung Nguyen, Jing Peng, Zhong Zheng, Mark Merchant, Daniel P. Sutherlin, John J. Gaudino, Robert K

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 636 KB

english, 2013

2

[ASME ASME 2002 Pressure Vessels and Piping Conference - Vancouver, BC, Canada (August 5–9, 2002)] Thermal Hydraulic Problems, Sloshing Phenomena, and Extreme Loads on Structures - Single Chain Stochastic Polymer Modeling at High Strain Rates

Harstad, Eric N., Harlow, Francis H., Schreyer, Howard L.

Year:

2002

Language:

english

File:

PDF, 3.36 MB

english, 2002

3

Balancing Blood Sample Volume with 3Rs: Implementation and Best Practices for Small Molecule Toxicokinetic Assessments in Rats

Harstad, Eric, Andaya, Roxanne, Couch, Jessica, Ding, Xiao, Liang, Xiaorong, Liederer, Bianca M., Messick, Kirsten, Nguyen, Trung, Schweiger, Michelle, Tarrant, Jacqueline, Zhong, Shelly, Dean, Brian

Journal:

Year:

2016

Language:

english

File:

PDF, 299 KB

english, 2016

4

AIP Conference Proceedings [Author(s) SHOCK COMPRESSION OF CONDENSED MATTER - 2017: Proceedings of the Conference of the American Physical Society Topical Group on Shock Compression of Condensed Matter - St. Louis, MO, USA (9–14 July 2017)] - Computational investigation of in-flight temperature in shaped charge jets and explosively formed penetrators

Sable, Peter, Helminiak, Nathaniel, Gullerud, Arne, Harstad, Eric, Hollenshead, Jeromy, Hertel, Eugene S.

Year:

2018

Language:

english

File:

PDF, 1.59 MB

english, 2018

5

Tumor Necrosis Factor-α-Null Mice Are Not Resistant to Cadmium Chloride-Induced Hepatotoxicity

Eric B. Harstad, Curtis D. Klaassen

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 685 KB

english, 2002

6

DPP8 and DPP9 expression in cynomolgus monkey and Sprague Dawley rat tissues

Harstad, Eric. B., Rosenblum, Jonathan S., Gorrell, Mark D., Achanzar, William E., Minimo, Lauro, Wu, Jiangyue, Rosini-Marthaler, Laura, Gullo, Russell, Ordway, Nicole D., Kirby, Mark S., Chadwick, Kr

Journal:

Regulatory Peptides

Year:

2013

Language:

english

File:

PDF, 1.54 MB

english, 2013

7

Discovery of 5-Azaindazole (GNE-955) as a Potent Pan-Pim Inhibitor with Optimized Bioavailability

Wang, Xiaojing, Kolesnikov, Aleksandr, Tay, Suzanne, Chan, Grace, Chao, Qi, Do, Steven, Drummond, Jason, Ebens, Allen J., Liu, Ning, Ly, Justin Q., Harstad, Eric, Hu, Huiyong, Moffat, John G., Munugal

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.01 MB

english, 2017

8

iNOS-null mice are not resistant to cadmium chloride-induced hepatotoxicity

Eric B. Harstad, Curtis D. Klaassen

Journal:

Year:

2002

Language:

english

File:

PDF, 619 KB

english, 2002

9

Gadolinium Chloride Pretreatment Prevents Cadmium Chloride-Induced Liver Damage in Both Wild-Type and MT-Null Mice

Eric B. Harstad, Curtis D. Klaassen

Journal:

Toxicology and Applied Pharmacology

Year:

2002

Language:

english

File:

PDF, 647 KB

english, 2002

10

AIP Conference Proceedings [Author(s) SHOCK COMPRESSION OF CONDENSED MATTER - 2017: Proceedings of the Conference of the American Physical Society Topical Group on Shock Compression of Condensed Matter - St. Louis, MO, USA (9–14 July 2017)] - Dynamic shock response of an S2 glass/SC15 epoxy woven fabric composite material system

Key, Christopher T., Alexander, C. Scott, Harstad, Eric N., Schumacher, Shane C.

Year:

2018

Language:

english

File:

PDF, 1.07 MB

english, 2018

11

Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor

Wang, Aiying, Dorso, Charles, Kopcho, Lisa, Locke, Gregory, Langish, Robert, Harstad, Eric, Shipkova, Petia, Marcinkeviciene, Jovita, Hamann, Lawrence, Kirby, Mark S

Journal:

BMC Pharmacology

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

12

Discovery of novel pyrazolo[1,5-a]pyrimidines as potent pan-Pim inhibitors by structure- and property-based drug design

Wang, Xiaojing, Magnuson, Steven, Pastor, Rich, Fan, Eric, Hu, Huiyong, Tsui, Vickie, Deng, Wei, Murray, Jeremy, Steffek, Micah, Wallweber, Heidi, Moffat, John, Drummond, Jason, Chan, Grace, Harstad,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.23 MB

english, 2013

13

Preclinical stereoselective disposition and toxicokinetics of two novel MET inhibitors

Liederer, Bianca M., Liu, Xingrong, Berezhkovskiy, Leonid M., Cain, Gary, Ding, Xiao, Gaudino, John, Kaus, Robert, Plise, Emile G., Sutherlin, Daniel P., Harstad, Eric B.

Journal:

Year:

2012

Language:

english

File:

PDF, 806 KB

english, 2012

14

An Algorithm for Evaluating Potential Tissue Drug Distribution in Toxicology Studies from Readily Available Pharmacokinetic Parameters

Poulin, Patrick, Dambach, Donna M., Hartley, Dylan H., Ford, Kevin, Theil, Frank-Peter, Harstad, Eric, Halladay, Jason, Choo, Edna, Boggs, Jason, Liederer, Bianca M., Dean, Brian, Diaz, Dolores

Journal:

Journal of Pharmaceutical Sciences

Year:

2013

Language:

english

File:

PDF, 954 KB

english, 2013

15

AIP Conference Proceedings [Author(s) SHOCK COMPRESSION OF CONDENSED MATTER - 2017: Proceedings of the Conference of the American Physical Society Topical Group on Shock Compression of Condensed Matter - St. Louis, MO, USA (9–14 July 2017)] - Evaluation of XHVRB for capturing shock desensitization

Tuttle, Leah, Schmitt, Robert, Kittell, Dave, Harstad, Eric

Year:

2018

Language:

english

File:

PDF, 1.90 MB

english, 2018

16

Regulation of neurokinin-1 receptor expression by GABAB receptor agonists

S.J. Enna, Eric B. Harstad, Kenneth E. McCarson

Journal:

Year:

1998

Language:

english

File:

PDF, 390 KB

english, 1998

17

A design of inverse Taylor projectiles using material simulation

Tonks, Michael, Harstad, Eric, Maudlin, Paul, Trujillo, Carl

Journal:

Modelling and Simulation in Materials Science and Engineering

Year:

2008

Language:

english

File:

PDF, 442 KB

english, 2008

18

Two stochastic mean-field polycrystal plasticity methods

Michael R. Tonks, John F. Bingert, Curt A. Bronkhorst, Eric N. Harstad, Daniel A. Tortorelli

Journal:

Journal of the Mechanics and Physics of Solids

Year:

2009

Language:

english

File:

PDF, 816 KB

english, 2009

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